Table 3.
Site investigators (SIs) reasons for believing that subjects were HD gene‐positive by CAG and diagnostic confidence level (DCL)
| Reasons for believing that subject is gene positive | CAG < 37 N = 434 visits | CAG ≥ 37 N = 906 visits | ||
|---|---|---|---|---|
| DCL 0–2 N = 391 visits | DCL 3–4 N = 43 visits | DCL 0–2 N = 510 visits | DCL 3–4 N = 394 visits | |
| Motor | 290 (75%) | 36 (84%) | 410 (81%) | 390 (99%) |
| Cognitive | 49 (13%) | 13 (32%) | 81 (16%) | 189 (48%) |
| Behavioral | 130 (34%) | 23 (56%) | 169 (34%) | 176 (45%) |
| Functional | 17 (4%) | 0 (0%) | 32 (6%) | 108 (28%) |
Subject visits where site investigator thought that the subject was gene positive: multiple visits per subject (N = 1340 visits). SI motor evaluation and reasons for believing that subject is gene positive; multiple reasons could be selected.