Table 7.

Overview of the biosynthetic compounds predicted in the NWUMFkBS10.5 genome

Biosynthetic compound	Cluster located	Biomedical/Biocontrol function	Reference
Mycosubtilin	6	Antifungal, hemolytic, and limited antibacterial activity	Duitman et al. (2007), Leclère et al. (2005)
Fengycin and Plipastatin	6	Broad‐spectrum antifungal and antitumoral agent	Cochrane and Vederas (2016), Vanittanakom, Loeffler, Koch, and Jung (1986)
Surfactin	13	Antibacterial, antifungal, antiviral, antimycoplasma, antitumoral, insecticidal, anticoagulant activities, and enzyme inhibitors	Mnif and Ghribi (2015), Ongena and Jacques (2008)
Iturin	6	Antibacterial and antifungal activity	Dunlap et al. (2013), Ongena and Jacques (2008)
Polymyxin	6	Antibacterial, antifungal, and Immuno‐modulating activity	Cochrane et al. (2016)
Sessilin	10	Antifungal activity	D’Aes et al. (2011), Olorunleke, Hua, Kieu, Ma, and Höfte (2015)
Bananamides	10	Unspecified	Nguyen et al. (2016)
Cichopeptin	10	Limited information	Huang et al. (2015)
Viscosin	10	Biosurfactant	Alsohim et al. (2014), Bonnichsen et al. (2015)
Taiwachelin, tolaasinand, orfamide	10	Iron chelation, therapeutic peptide, insecticidal biosurfactant, and elicitor of induced systemic resistance	Andolfi, Cimmino, Cantore, Iacobellis, and Evidente (2008), Jang et al. (2013), Kreutzer, Kage, and Nett (2012), Ma, Ongena, and Höfte (2017)
Mersacidin	16	Antibacterial	Abriouel, Franz, Ben Omar, and Gálvez (2011)
Bacitracin and bacilysin	15	Limited use as animal growth promoter, topical antibiotic, antibacterial, and antifungal	Mousa and Raizada (2015), Phillips (1999)
Bacillibactin, paenibactin, griseobactin, heterobactin, mirubactin, myxochelin, vanchrobactin	14	Iron chelation and anticancer agent	Balado, Osorio, and Lemos (2008), Giessen et al. (2012), Patzer and Braun (2010), Sandy et al. (2010), Wen et al. (2011)
Amylocyclicin	1	Antibacterial and plant growth promoter	Scholz et al. (2014)
Lichenysin	13	Biosurfactant	Grangemard, Bonmatin, Bernillon, Das, and Peypoux (1999)
Basiliskamides	13	Antifungal	Theodore et al. (2014)
Difficidin	11, 7, 4	Broad‐spectrum antibacterial compound	Chen et al. (2009), Mousa and Raizada (2015)
Kalimantacin/batumin and oocydin A	11, 7, 5	Antibacterial and antifungal haterumalide	Matilla, Leeper, and Salmond (2015), Mattheus et al. (2010), Tokunaga et al., (1996)
Sorangicin	11, 7	Antibacterial macrolide antibiotic	Campbell et al. (2005)
Elansolid	7	Antibiotic (Bactericidal)	Steinmetz et al. (2011)
Myxovirescin	7, 5	Antibiotic (Bactericidal)	Xiao, Gerth, Müller, and Wall (2012)
Phormidolide, thiomarinol, and mupirocin	5	Antitumor agent and antibacterial metabolite/clinical antibiotic	Mousa and Raizada (2015), Murphy et al. (2014)
Paenilarvins, tridecaptin, and paenibacterin	6	Antifungal, antitumor agent, and antibiotic (Bactericidal)	Cochrane et al. (2016), Hertlein et al. (2016), Huang, Guo, and Yousef (2014), Huang and Yousef (2014)