Table 2.
CSF LEUCOCYTE (95% CI) | CSF PROTEIN (95% CI) | CSF GLUCOSE (95% CI) | CSF ERYTHROCYTE (95% CI) | |
---|---|---|---|---|
True Positive | 117 | 285 | 315 | 99 |
False Positive | 09 | 33 | 03 | 00 |
False Negative | 00 | 03 | 06 | 00 |
True Negative | 234 | 39 | 36 | 261 |
Sensitivity | 100% (90.9%–100%) | 98.9% (94.3%–99.9%) | 98.1% (93.4%–99.8%) | 100% (89.4%–100%) |
Specificity | 96.3% (89.6%–99.2%) | 54.2% (32.8%–74.5%) | 92.3% (63.9%–99.8%) | 100% (95.9%–100%) |
Positive Likelihood Ratio | 27 (8.9–81.9) | 2.2 (1.4–3.34) | 12.8 (1.9–83.8) | 00 |
Negative Likelihood Ratio | 00 | 0.02 (0.00–0.14) | 0.02 (0.01–0.08) | 00 |
Disease prevalence | 32.5% (24.2%–41.6%) | 80% (71.72%–86.75%) | 89.2% (82.2%–94.1%) | 27.5% (19.8 %–36.4%) |
Positive Predictive Value (PPV) | 92.9% (80.5%–98.5%) | 89.6% (82.19%–94.70%) | 99.1% (94.9%–99.9%) | 100% (89.4%–100%) |
Negative Predictive Value (NPV) | 100% (95.38%–100.00%) | 92.9% (66.13%–99.82%) | 85.7% (57.2%–98.2%) | 100% (95.9%–100%) |
Area under the ROC curve (AUC) | 0.92 | 0.714 | 0.887 | 1.000 |
Standard Error | 0.028 | 0.0705 | 0.0828 | 0.000 |