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. 2019 Jan 11;219(10):1536–1544. doi: 10.1093/infdis/jiy578

Table 5.

Improvement/Resolution of Symptoms by Study Day (Shionogi Database)

Nonventilated HABP
Improvement Doripenem, % (no./No.) Piperacillin-Tazobactam, % (no./No.)
Day 5 Day 7 Day 5 Day 7
Improvement in at least 2 symptoms 71.4 (80/112) 83.8 (78/93) 77.6 (90/116) 82.1 (78/95)
Improvement in 3 symptoms 69.7 (23/33) 65.5 (19/29) 79.1 (34/43) 89.2 (33/37)

No. indicates the number of subjects with 2 or 3 symptoms at baseline and with these same symptoms assessed at the specified postbaseline visit, and includes subjects who died (ie, patients who died are considered to not have had an improvement in symptoms).

Abbreviation: HABP, hospital-acquired bacterial pneumonia.