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. 2019 Jun 6;10:693. doi: 10.3389/fphys.2019.00693

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Copyright © 2019 Karey, Pan, Morris, Bruun, Lein and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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24-h time domain HRV parameters using different exclusion criteria (15%, 20%, 1.5 SD, and 2 SD) in mice (left) and rats (right). Data are expressed as % difference from manual exclusion. Overall, the HRV parameters were closer to the manual exclusion method using the % change method, compared to the SD-exclusion method. In addition, the SD methods had more variable estimates. 20% criterion had better rMSSD estimate than the 15% criterion in mice but had similar results in rats.