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. 2019 Jun 7;6:505–513. doi: 10.1016/j.toxrep.2019.06.001

Table 2.

Role of GA in tissue biomarker changes.

Groups NBT reduction (pM / Min / mg of tissue) MPO (unit / Min /mg of protein)
Control 3.53 ± 1.73 14.81 ± 1.91
GA per se 3.27 ± 1.21 15.49 ± 1.17
PT 28.81 ± 0.78* 95.39 ± 1.94*
PT + GA (20) 9.91 ± 1.52# 43.79 ± 2.82#
PT + GA (40) 5.04 ± 1.17# 37.94 ± 2.61#
PT + PreG (5) 4.62 ± 0.71# 19.79 ± 1.85#

Digits in parenthesis indicate dose in mg/kg. Data were expressed as mean ± SD, n = 6 mice per group. *p < 0.05 vs control group. #p < 0.05 vs PT control group. Abbreviation: GA, gallic acid, PT, paclitaxel; PreG, pregabalin; NBT, nitroblue tetrazolium; and MPO, myeloperoxidase.