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. 2019 May 14;17(5):291. doi: 10.3390/md17050291

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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(A) Activated partial thromboplastin time (APTT), (B) prothrombin time (PT), and (C) thrombin time (TT) assays of ULVAN-01 (Δ), ULVAN-02 (▼), unfractionated heparin (UFH) (○), and Lovenox^® (●). The clotting times of the plasma in the absence of fractions (negative control, 0.9% NaCl) were (A) 38.2 s, (B) 13.1 s, and (C) 12.9 s. The maximum clotting times measured by the coagulometer were (A) 120 s, (B) 70 s, and (C) 60 s (no coagulation within this time range). Data shown as the mean +/−SD, n = 6.