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KLK12 restrains intracellular survival of M. bovis in murine BMDMs. Murine BMDMs were transfected with KLK12 siRNA and negative control siRNA (20 μM). After 48 h of transfection, the BMDMs were infected with M. bovis C68004 at a MOI of 10 and incubated for indicated times (6 and 24 h) and bacterial survival was measured by the CFU assay. Data represent the mean ± SD of three independent experiments (** p < 0.01).
