Cell viability of ARPE19 cells challenged with 500 µM TBHP after incubation with fucoidan from (a) Saccharina latissima (SL), (b) Laminaria digitata (LD), (c) Fucus serratus (FS), (d) Fucus vesiculosus (FV), (e) Fucus distichus subsp. evanescens (FE). Cell viability was measured by MTS assay and is depicted as mean and standard deviation, with the control set as 100%. Only SL fucoidan displayed a protective effect, while FS and FE fucoidans reduced cell viability. Significance was evaluated with Friedman’s ANOVA and subsequent Student’s t-test, ++ p < 0.01, +++ p < 0.001, for protective effects against 500 µM TBHP, * p < 0.05, ** p < 0.01 and *** p < 0.001 for exacerbating effects against 500 µM TBHP (n = 8).