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Pharmacokinetics Parameters of DFX117 after po administration a.
| Parameters | T1/2 (h) | Tmax (h) | Cmax (ng/mL) | AUCall (h·ng/mL) | MRTinf_obs (h) |
|---|---|---|---|---|---|
| Value (po b) | 2.1 | 0.3 | 4504.3 | 3340.6 | 2.2 |
a Values are the average of three runs. Vehicle: DMSO: PEG: saline = 1:4:5. b Dose: po at 10 mg/mL. T1/2, half-life; Cmax, maximum concentration; Tmax, time of maximum concentration; AUCall (h·ng/mL), area under the plasma concentration time curve.
