Table 6.
HCP5–miRNA–protein coding gene regulator interactions.
| Antioncogenic miRNA | HCP5 Action | Gene Symbol and Up- or Downregulated | Cancer Type | Reference |
|---|---|---|---|---|
| miR-203 | sponge | TGFb/SMAD3 | Lung | [56] |
| miR-106b-5p | network | CTSS/FGL2 | Lung | [130] |
| miR-17-5b | network | PDCD1LG2/PDL2 | Lung | [130] |
| miR-126 | GSR/ASCL1 ↑ | Lung metastasis | [152] | |
| MET/GRM8/DACH1 ↓ | Lung metastasis | [152] | ||
| miR-139 | absorption | RUNX1 ↑ | Glioma | [150] |
| miR-139-5p | ZEB1 | Colorectal | [153] | |
| APIG1 ↓ | Colon | [154] | ||
| miR-22-3p | sponge | ST6GAL2 ↑ | Thyroid | [155] |
| mi-186-5p | sponge | ST6GAL2 ↑ | Thyroid | [155] |
| miR-216a-5p | sponge | ST6GAL2 ↑ | Thyroid | [155] |
| miR-15a | adsorption | MACC1 ↑ | Cervical | [156] |
| miR-155 | sponge | Complement genes | Breast | [157] |
| miR-128 | sponge | MACC1 ↑ | Gastric | [163] |
| miR-101 | sponge | NDUFB6 ↓ | Gastric | [163] |
| miR-103a | sponge | NDUFB6 ↓ | Gastric | [163] |
| 24 different mIR | ceRNA | TAP1 ↑ | Lymphoma | [164] |
| ceRNA | PSMB9 ↑ | Lymphoma | [164] | |
| ceRNA | KLF2 ↑ | Lymphoma | [164] | |
| ceRNA | GIPC1 ↑ | Lymphoma | [164] | |
| ceRNA | ETN3A3 ↑ | Lymphoma | [164] | |
| ceRNA | ETN3A1 ↑ | Lymphoma | [164] | |
| ceRNA | CD47 ↑ | Lymphoma | [164] | |
| ceRNA | CCDC50 ↑ | Lymphoma | [164] | |
| ceRNA | LMBR1L ↑ | Lymphoma | [164] | |
| ceRNA | HERC6 ↑ | Lymphoma | [164] |
↑ is upregulation and ↓ is downregulation.