Table 2.
TCGA analysis of up-regulated and down-regulated miRNAs in the tumor compared to the normal samples.
| miRNA ID | miRNA Name | FC Cancer vs Normal | p-Value * |
|---|---|---|---|
| Up-regulated | |||
| MIMAT0000226 | hsa-miR-196a-5p | 12.145 | 3.12 × 10−19 |
| MIMAT0001080 | hsa-miR-196b-5p | 11.639 | 5.43 × 10−20 |
| MIMAT0000267 | hsa-miR-210-3p | 9.733 | 1.18 × 10−9 |
| MIMAT0000089 | hsa-miR-31-5p | 7.684 | 8.42 × 10−12 |
| MIMAT0004784 | hsa-miR-455-3p | 7.165 | 9.21 × 10−18 |
| MIMAT0005923 | hsa-miR-1269a | 5.899 | 1.99 × 10−11 |
| MIMAT0000102 | hsa-miR-105-5p | 5.510 | 9.64 × 10−13 |
| MIMAT0004504 | hsa-miR-31-3p | 5.298 | 1.59 × 10−9 |
| MIMAT0003882 | hsa-miR-767-5p | 5.294 | 5.40 × 10−13 |
| MIMAT0000281 | hsa-miR-224-5p | 4.789 | 5.39 × 10−11 |
| MIMAT0002874 | hsa-miR-503-5p | 4.044 | 3.86 × 10−19 |
| MIMAT0002819 | hsa-miR-193b-3p | 3.407 | 8.17 × 10−15 |
| MIMAT0005951 | hsa-miR-1307-3p | 3.395 | 1.14 × 10−11 |
| MIMAT0000076 | hsa-miR-21-5p | 3.209 | 3.05 × 10−10 |
| MIMAT0000266 | hsa-miR-205-5p | 3.040 | 1.64 × 10−5 |
| MIMAT0016895 | hsa-miR-2355-5p | 3.023 | 6.22 × 10−14 |
| MIMAT0004987 | hsa-miR-944 | 3.020 | 7.56 × 10−7 |
| MIMAT0005797 | hsa-miR-1301-3p | 2.902 | 6.39 × 10−17 |
| MIMAT0000761 | hsa-miR-324-5p | 2.878 | 7.41 × 10−12 |
| MIMAT0000758 | hsa-miR-135b-5p | 2.859 | 4.08 × 10−8 |
| MIMAT0001341 | hsa-miR-424-5p | 2.856 | 4.57 × 10−13 |
| MIMAT0000072 | hsa-miR-18a-5p | 2.829 | 8.10 × 10−10 |
| MIMAT0001545 | hsa-miR-450a-5p | 2.828 | 1.20 × 10−15 |
| MIMAT0000688 | hsa-miR-301a-3p | 2.807 | 5.32 × 10−13 |
| MIMAT0003150 | hsa-miR-455-5p | 2.799 | 3.50 × 10−12 |
| Down-regulated | |||
| MIMAT0002870 | hsa-miR-499a-5p | −3.296 | 3.76 × 10−5 |
| MIMAT0000733 | hsa-miR-379-5p | −3.298 | 1.29 × 10−10 |
| MIMAT0002890 | hsa-miR-299-5p | −3.504 | 8.97 × 10−7 |
| MIMAT0000461 | hsa-miR-195-5p | −3.510 | 7.79 × 10−14 |
| MIMAT0022721 | hsa-miR-1247-3p | −3.553 | 3.40 × 10−7 |
| MIMAT0016847 | hsa-miR-378c | −3.670 | 4.61 × 10−8 |
| MIMAT0002171 | hsa-miR-410-3p | −3.684 | 9.33 × 10−12 |
| MIMAT0004603 | hsa-miR-125b-2-3p | −3.694 | 1.52 × 10−18 |
| MIMAT0004606 | hsa-miR-136-3p | −3.797 | 1.08 × 10−12 |
| MIMAT0004550 | hsa-miR-30c-2-3p | −3.881 | 1.03 × 10−12 |
| MIMAT0004552 | hsa-miR-139-3p | −3.937 | 3.02 × 10−14 |
| MIMAT0000099 | hsa-miR-101-3p | −4.017 | 3.64 × 10−23 |
| MIMAT0000087 | hsa-miR-30a-5p | −4.132 | 6.93 × 10−14 |
| MIMAT0003329 | hsa-miR-411-5p | −4.160 | 2.03 × 10−10 |
| MIMAT0000265 | hsa-miR-204-5p | −4.519 | 1.28 × 10−17 |
| MIMAT0000681 | hsa-miR-29c-3p | −4.539 | 5.24 × 10−17 |
| MIMAT0000064 | hsa-let-7c-5p | −4.674 | 3.68 × 10−22 |
| MIMAT0000462 | hsa-miR-206 | −5.228 | 4.62 × 10−3 |
| MIMAT0000736 | hsa-miR-381-3p | −5.293 | 5.06 × 10−8 |
| MIMAT0000770 | hsa-miR-133b | −5.580 | 3.66 × 10−4 |
| MIMAT0000088 | hsa-miR-30a-3p | −5.696 | 2.66 × 10−13 |
| MIMAT0000097 | hsa-miR-99a-5p | −5.746 | 1.85 × 10−27 |
| MIMAT0000427 | hsa-miR-133a-3p | −7.055 | 2.93 × 10−4 |
| MIMAT0000416 | hsa-miR-1-3p | −10.663 | 8.80 × 10−6 |
| MIMAT0000728 | hsa-miR-375-3p | −18.183 | 1.3 3 × 10−11 |
In bold the miRNAs in common with the results of the GEO DataSets analysis; * p-values were calculated by Student’s t-test.