Figure 8.
Effects of dietary tryptophan supplementation on mRNA expression of genes involved in mitochondrial biogenesis and mtDNA content in the jejunum of piglets challenged with diquat. (A) NRF1, nuclear respiratory factor 1; (B) TFAM, transcription factor A, mitochondrial; (C) PPARGC1A, peroxisome proliferative activated receptor gamma coactivator 1 alpha; (D) SIRT1, sirtuin 1; (E) SSBP1, single stranded DNA binding protein 1; (F) POLRMT, DNA-directed RNA polymerase, mitochondrial; (G) mtDNA, mitochondrial DNA. Data are means ± standard error; n = 8 for each group. Mean values sharing different superscripts within the same row differ significantly (p < 0.05). Control, piglets fed the basal diet without diquat injection; diquat, piglets fed the basal diet and challenged with diquat; 0.15% Trp + diquat, piglets fed the 0.15% supplemented diet and treated with diquat.