Table 5.
Linear mixed effects models showing factors associated with changes in current ACE-R scores at each time point.
| Variable | Variation in ACE-R with variable at: | Change in ACE-R between: | Change in ACE-R with variable at: | ||||||
|---|---|---|---|---|---|---|---|---|---|
| 1–3 Months | 1–3 Months and 1 Year | 1 Year | |||||||
| B | 95% CI | p | B | 95% CI | p | B | 95% CI | p | |
| Age | −0.239 | (−0.345, −0.133) | <0.001 | −2.191 | (−7.337, 2.954) | 0.401 | −0.202 | (−0.311, −0.093) | <0.001 |
| Sex (male) | −0.370 | (−2.417, 1.677) | 0.721 | −0.001 | (−1.389, 1.387) | 0.999 | −0.030 | (−2.150, 2.090) | 0.977 |
| Baseline Fazekas | −0.221 | (−0.915, 0.473) | 0.529 | 0.207 | (1.597, 2.011) | 0.820 | −0.222 | (−0.937, 0.494) | 0.541 |
| Stroke subtype (lacunar) | −0.327 | (−2.433, 1778) | 0.759 | −0.020 | (−1.177, 1.137) | 0.973 | 0.191 | (−1.995, 2.377) | 0.863 |
| NIHSS | −0.609 | (−1.541, 0.323) | 0.198 | −0.536 | (−1.683, 0.612) | 0.357 | 0.115 | (−0.840, 1.070) | 0.812 |
| Hypertension (yes) | 2.761 | (0.499, 5.033) | 0.018 | 0.073 | (−1.601, 1.746) | 0.932 | 2.943 | (0.605, 5.280) | 0.014 |
| Smoker (yes) | 0.388 | (−1.859, 2.635) | 0.733 | 0.595 | (−0.452, 1.642) | 0.263 | −0.835 | (−3.165, 1.494) | 0.479 |
| NART IQ | 0.290 | (0.171, 0.408) | 0.000 | −6.217 | (−18.303, 5.869) | 0.310 | 0.345 | (0.229, 0.461) | <0.001 |
| Years of education | 0.407 | (0.026, 0.788) | 0.037 | −2.157 | (−5.616, 1.302) | 0.219 | 0.603 | (0.229, 0.977) | 0.002 |
| 1 Year | 1 and 3 Years | 3 Years | |||||||
| Age | −0.054 | (−0.196, 0.087) | 0.447 | 5.771 | (2.560, 8.981) | 0.001 | −0.137 | (−0.255, −0.019) | 0.024 |
| Sex (male) | 1.016 | (−1,928, 3.960) | 0.495 | 0.803 | (−0.114, 1.720) | 0.085 | 0.370 | (−1.882, 2.622) | 0.745 |
| Baseline Fazekas | −0.123 | (−1.088, 0.842) | 0.801 | 1.250 | (0.018, 2.482) | 0.047 | −0.407 | (−1.167, 0.353) | 0.291 |
| Stroke subtype (lacunar) | −1.008 | (−3.990, 1.974) | 0.504 | <0.001 | (−0.783, 0.783) | 0.999 | 0.022 | (−2.291, 2.335) | 0.985 |
| NIHSS | 0.227 | (−1.063, 1.517) | 0.727 | 0.683 | (−0.138, 1.504) | 0.102 | −0.005 | (−1.011, 1.000) | 0.992 |
| Hypertension (yes) | 2.378 | (−0.875, 5.632) | 0.150 | 0.444 | (−0.709, 1.598) | 0.446 | 2.367 | (−0.108, 4.843) | 0.061 |
| Smoker (yes) | −1.491 | (−4.670, 1.689) | 0.354 | 0.089 | (−0.619, 0.796) | 0.804 | −0.226 | (−2.697, 2.245) | 0.856 |
| NART IQ | 0.380 | (0.211, 0.549) | <0.001 | −3.704 | (−11.427, 4.020) | 0.343 | 0.416 | (0.286, 0.546) | <0.001 |
| Years of education | 0.548 | (0.064, 1.032) | 0.027 | 1.019 | (−1.312, 3.350) | 0.387 | 0.501 | (0.113, 0.888) | 0.012 |
All estimates are adjusted for the other variables in the model. Each row represents an individual, but strongly related, overlapping model. Full tables for each model can be found in Table S4.