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. 2019 Apr 26;11(5):240. doi: 10.3390/toxins11050240

Table 2.

Cumulative TTX testing results for shellfish produced and harvested in the EU, which have not been assessed in the EFSA TTX opinion [16], reported by different countries using LC-MS/MS analysis.

Country Year(s) of Sampling Shellfish Species Samples Tested (n) 1 TTX-Positive Samples (n) 2 Maximum TTXs Concentration (μg/kg) Reference
Italy 2017 Mussels (Mytilus galloprovincialis) 2 1 541 [47]
Wedge clams (Donax trunculus) 1 0 n.d. 3
2018 Mussels (Mytilus galloprovincialis) n.r. 4 2 216 [48]
2015–2017 Mussels (Mytilus galloprovincialis) 23 14 6.4 [46]
Clams (Venerupis decussata) 2 0 n.d.
Netherlands 2015–October 2018 Mussels (Mytilus edulis) 1085 38 101 [29,49]
Oysters (Crassostrea gigas) 246 52 253
Razor clams (Ensis spp.) 113 0 n.d.
Cockles (Cerastoderma edule) 91 0 n.d.
Spain 2017 Mussels 5 258 0 n.d. [50]
Oysters 5 28 6 1 0.9
Cockles 5 1 2.3
2018 Mussels, Oysters, Cockles 5 72 6 0 n.d. [51]
France 2018 Mussels 5 108 0 n.d. [52]
Oysters 5 24 0 n.d.
Ireland 2012–2016 14 shellfish species, including gastropods and grazers 5 508 6 0 7 n.d. [53,54,55,56]
UK 2014–2016 Mussels (Mytilus edulis) 1222 6 57 8 73 [22]
Pacific oysters (Crassostrea gigas) 253
Native oysters (Ostrea edulis) ~ 80
Cockles (Cerastoderma edule) n.d.
Hard clams (Mercenaria mercenaria) 72
Surf clams (Spisula solida) n.d.
King scallops (whole) (Pecten maximus) n.d.
King scallops (adductor & roe) (Pecten maximus) n.d.

1 n = number of samples; 2 TTX-positive = above method Limit of Detection (LOD), unless otherwise indicated; 3 n.d. = not detected; 4 n.r. = not reported; 5 Individual numbers of samples by species not reported; 6 Species scientific name(s) not reported; 7 TTX-positive = above method Limit of Quantification (LOQ) = 40 μg/kg; 8 TTX-positive = above method Limit of Reporting (LOR) = 2 μg/kg.