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. 2019 May 5;8(5):417. doi: 10.3390/cells8050417
OXPHOS Oxidative phosphorylation system
NAFLD Non-alcoholic fatty liver disease
NASH Non-alcoholic steatohepatitis
HCC Hepatocellular carcinoma
mTOR Mammalian target of rapamycin
PI3K Phosphoinositide 3-kinase
AKT Protein kinase B
mTORC1 Mammalian target of rapamycin complex 1
mTORC2 Mammalian target of rapamycin complex 2
SREBP-1 Sterol regulatory element-binding protein 1
PPARs Peroxisome Proliferator Activated Receptor
PGC-1s Peroxisome proliferator-activated receptor gamma coactivator 1
TZD Thiazolidinedione
FA Fatty acid
FAO Fatty acid oxidation
CPT-1 Carnitine Palmitoyltransferase 1
CPT-2 Carnitine Palmitoyltransferase 2
TCA Tricarboxylic acid cycle
HMG-CoA β-Hydroxy β-methylglutaryl-CoA
UCP Uncoupling Protein
DEN Diethylnitrosamine
NF-kB Nuclear Factor Kappa B
HADHA Hydroxyacyl-CoA Dehydrogenase Trifunctional Multienzyme Complex Subunit Alpha
MLYCD Malonyl-CoA Decarboxylase
ACC1 Acetyl-CoA carboxylase 1
AMPK 5′ adenosine monophosphate-activated protein kinase
CTNNB1 Catenin Beta 1
ACAC Acetyl-CoA Carboxylase
GLUT2 Glucose transporter 2
GK Glycerol Kinase
FASN Fatty acid synthase
ACC2 Acetyl-CoA carboxylase 2
SCD1 Stearoyl-CoA Desaturase 1
PEPCK Phosphoenolpyruvate carboxykinase
FASN Fatty Acid Synthase
HNF-4 Hepatocyte Nuclear Factor 4 Alpha
PPP Pentose-Phosphate-Pathway
GLS1 Glutaminase
PTEN Phosphatase and Tensin Homolog
HK Hexokinase
PKM2 Pyruvate Kinase M2
MEK Mitogen-activated Protein Kinase Kinase
ERK Extracellular signal–regulated Kinases
PFKFB4 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 4
MCAD Medium-chain acyl-CoA dehydrogenase
ERR Estrogen Related Receptors
NRF Nuclear Respiratory Factor
GR Glucocorticoid receptor
ER Estrogen Receptor
TFB1M Transcription Factor B1, Mitochondrial
TFB2M Transcription Factor B2, Mitochondrial
TFAM Transcription Factor A, Mitochondrial
HNFα Hepatocyte Nuclear Factor Alpha
FOXO1 Forkhead Box O1
CREB CAMP Responsive Element Binding Protein
PEPCK Phosphoenolpyruvate Carboxykinase
G6PD Glucose-6-Phosphate Dehydrogenase
LXRα Liver X Receptor Alpha
SIRT1 Sirtuin 1
YAP Yes-associated protein 1
JNK c-Jun N-terminal Kinases
BNIP3 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
CaMKII Ca2+/calmodulin-dependent protein kinases II
NRF2 Nuclear factor erythroid 2 related factor 2
AREs Antioxidant response elements
KEAP1 Kelchlike ECH-associated protein 1
CUL3 Cullin 3
RBX1 Ring-Box 1
PKCδ Protein kinase C delta
sMAF small Maf proteins
NQO-1 NADPH quinone oxidoreductase
GSTs Glutathione S-transferases
HMOX1 Heme oxygenase-1
HK II Hexokinase 2
CS Citrate Synthase
TRAP1 TNF Receptor Associated Protein 1
HIF-1α Hypoxia Inducible Factor 1 Subunit Alpha
HIFs Hypoxia Inducible Factors
HIF-1β Hypoxia Inducible Factor 1 Subunit Beta
PHD2 α-ketoglutarate-dependent prolyl hydroxylase 2 PHD2
VHL von Hippel-Lindau ubiquitin ligase
HREs Hypoxia Response Elements
HDAC NAD+-dependent histone deacetylases
LDH Lactate dehydrogenase
FXR Farnesoid X Receptor
CLOCK Clock Circadian Regulator
BMAL Brain and Muscle ARNT-Like
PER2 Period Circadian Regulator 2
GCN5 General control of amino acid synthesis 5
MFN-1 Mitofusin 1
MFN-2 Mitofusin 2
FAK Focal Adhesion Kinase
Drp1 Dynamin-1-like Protein
GSK-5b Glycogen Synthase Kinase 5 Beta
SOD2 Superoxide Dismutase 2
MMP2 Matrix Metallopeptidase 2
GSTP1 Glutathione S-transferase pi 1
LCAD Long-chain acyl-coenzyme A (acyl-CoA) dehydrogenase
LIHC Liver Hepatocellular Carcinoma
RASSF1 Ras Association Domain Family Member 1
GATA4 GATA Binding Protein 4
CDKL2 Cyclin Dependent Kinase Like 2
FH Fumarate dehydrogenase
SDH Succinate dehydrogenase
JHDMs Jumonji-C histone demethylases
TET Ten-eleven translocation methylcytosine dioxygenase