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. 2019 May 11;8(5):447. doi: 10.3390/cells8050447

Figure 1.

Figure 1

Licochalcone A (LA) reduced body weight in high-fat diet (HFD)-induced obese mice. (A) Male mice were fed an HFD (containing 60% fat) for 16 weeks, and administered DMSO, 5 mg/kg licochalcone A (LA5), or 10 mg/kg licochalcone A (LA10) by intraperitoneal injection (I.P.) twice a week from week 4 to 16. (B) Weight gain was measured for 16 weeks. (C) The appearance of the animal and (D) weight gain measured in the last week. (E) Food intake monitored each day. Data are presented as the mean ± SEM; n = 12. * p < 0.05, ** p < 0.01 compared with mice with HFD-induced obesity.