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. 2019 May 11;8(5):447. doi: 10.3390/cells8050447

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of licochalcone A (LA) on lipid metabolism in mouse liver tissue. (A) Expression of transcription factors associated with adipogenesis and lipogenesis, (B) lipolysis, (C) β-oxidation, and (D) the sirt-1/AMPK pathway were detected by Western blot. (E,F) The fold expression levels were measured relative to the expression of β-actin. Three independent experiments were analyzed using β-actin as an internal control. The data are presented as the mean ± SEM. * p < 0.05, ** p < 0.01 compared to the HFD group.