Table 1.
Patient characteristics.
| Characteristics | Number of Patients (%) | p Value | ||
|---|---|---|---|---|
| Non-SCNRT | SCNRT | |||
| (n = 745) | (n = 376) | |||
| Age (years) | ≤45 | 442 (59.3) | 221 (58.8) | 0.859 |
| >45 | 303 (40.7) | 155 (41.2) | ||
| OP site | Left | 343 (46.0) | 193 (51.3) | 0.094 |
| Right | 402 (54.0) | 183 (48.7) | ||
| Pathology | IDC | 702 (94.2) | 346 (92.0) | 0.157 |
| Others | 43 (5.8) | 30 (8.0) | ||
| T stage | T1 | 388 (52.1) | 181 (48.1) | 0.282 |
| T2 | 351 (47.1) | 192 (51.1) | ||
| T3 | 6 (0.8) | 2 (0.5) | ||
| T4 | 0 (0.0) | 1 (0.3) | ||
| Number of | Single | 615 (82.6) | 318 (84.6) | 0.392 |
| tumors | Multiple | 130 (17.4) | 58 (15.4) | |
| Resection | Clear | 682 (92.2) | 351 (93.9) | 0.588 |
| margin | Less than 1 mm | 51 (6.9) | 20 (5.3) | |
| Positive | 7 (0.9) | 3 (0.8) | ||
| Unknown | 5 | 2 | ||
| EIC | (−) | 344 (71.2) | 225 (63.9) | 0.025 |
| (+) | 139 (28.8) | 127 (36.1) | ||
| Unknown | 262 | 24 | ||
| LVI | (−) | 360 (49.0) | 81 (24.0) | <0.001 |
| (+) | 375 (51.0) | 256 (76.0) | ||
| Unknown | 10 | 39 | ||
| HG | I or II | 452 (61.9) | 235 (63.0) | 0.725 |
| III | 278 (38.1) | 138 (37.0) | ||
| Unknown | 15 | 3 | ||
| Anti-HER2 | (−) | 678 (91.0) | 339 (90.2) | 0.644 |
| therapy | (+) | 67 (9.0) | 37 (9.8) | |
| Dissected | <20 | 456 (61.2) | 245 (65.2) | 0.197 |
| LNs | ≥20 | 289 (38.8) | 131 (34.8) | |
| Number of | 1 | 509 (68.5) | 121 (32.2) | <0.001 |
| positive LNs | 2 | 161 (21.7) | 145 (38.6) | |
| 3 | 73 (9.8) | 110 (29.3) | ||
| Unknown | 2 | 0 | ||
| LNR | ≤0.10 | 599 (80.6) | 189 (50.3) | <0.001 |
| >0.10 | 144 (19.4) | 187 (49.7) | ||
| Unknown | 2 | 0 | ||
| ECE | (−) | 369 (52.4) | 92 (31.8) | <0.001 |
| (+) | 335 (47.6) | 197 (68.2) | ||
| Unknown | 41 | 87 | ||
| Hormone | (−) | 172 (23.1) | 86 (22.9) | 0.917 |
| therapy | (+) | 571 (76.9) | 290 (77.1) | |
| Unknown | 2 | 0 | ||
| Molecular | Luminal A | 498 (67.0) | 247 (65.7) | 0.19 |
| subtype | Luminal B | 71 (9.5) | 49 (13.0) | |
| HER2-enriched | 53 (7.1) | 17 (4.5) | ||
| Triple negative | 122 (16.4) | 63 (16.8) | ||
| Unknown | 1 | 0 | ||
Abbreviations: SCNRT, supraclavicular lymph node radiation therapy; OP, operation; IDC, invasive ductal carcinoma; EIC, extensive intraductal component; LVI, lymphovascular invasion; HG, histologic grade; HER2, human epidermal growth factor receptor 2; LNR, lymph-node ratio; ECE, extracapsular extension.