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. 2019 May 11;11(5):650. doi: 10.3390/cancers11050650

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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IL-17F reduces random migration in highly invasive HSC-3 cells. (A) 100 ng/mL of IL-17F reduced the random migration velocity of the highly invasive HSC-3 cell line compared with the non-stimulated controls. (B) 100 ng/mL of IL-17F reduced the accumulated distance of the highly invasive HSC-3 cell line compared with the non-stimulated controls. (C) IL-17F had no observable effect on the directed migration (wound density) of HSC-3 cells. (D–F) IL-17F did not affect the random (velocity and accumulated distance) or directed migration (wound density) of low-invasive SCC-25 cells. Data are presented as means ± standard deviations.