CNS |
Central nervous system |
EAAT1 and EAAT2 |
Excitatory amino acid transporters 1 and 2 |
GLAST |
Glutamate–aspartate transporter |
GLT-1 |
Glutamate transporter-1 |
ATP |
Adenosine triphosphate |
VGLUT1 and VGLUT2 |
Vesicular glutamate transporters 1 and 2 |
V-ATPase |
Vacuolar (H+) ATPase |
VAMP2 and VAMP3 |
Vesicle-associated membrane protein 2 and 3 |
ER |
Endoplasmic reticulum |
SNAP23 |
Soluble N-ethylmaleimide-sensitive factor attachment protein 23 |
HIV |
Human immunodeficiency virus |
MS |
Multiple sclerosis |
ALS |
Amyotrophic lateral sclerosis |
AD |
Alzheimer’s disease |
PD |
Parkinson’s disease |
NLRs |
NOD-like receptors |
NF-κB |
Nuclear factor-κB |
NLRX1 |
NOD-like receptor X1 |
IBD |
Inflammatory bowel disease |
EAE |
Experimental autoimmune encephalomyelitis |
WT |
Wild-type |
Nlrx1-/-
|
Nlrx1 knockout |
dFBS |
Deactivated fetal bovine serum |
DMSO |
Dimethyl sulfoxide |
HBSS |
Hank’s Balanced Salt Solution |
qPCR |
Quantitative real-time PCR |
PBS |
Phosphate-buffered saline |
ROS |
Reactive oxygen species |
DHR |
Dihydrorhodamine 123 |
mtDNA |
Mitochondrial DNA |
SEM |
Standard error of the mean |
2-APB |
2-Aminoethyl diphenylborinate |
IP3 |
Inositol-1,4,5-trisphosphate |
CsA |
Cyclosporin A |
PKC |
Protein kinase C |
AA |
Arachidonic acid |
SH group |
Sulfhydryl group |
TCA |
Tricarboxylic acid |