Table II.
Early changes in InsP3 are not significantly affected by treatment with the PLC inhibitor U73122
| Treatment | Gravistimulation for:
|
|
|---|---|---|
| 15 s | 30 s | |
| % | % | |
| Control | 100 | 100 |
| Inactive analog U73343 | 122 | 74 |
| PLC inhibitor U73122 | 107 | 82 |
The change in InsP3 in gravistimulated intact pulvinus tissue was determined after treatment with 0.5% (w/w) DMSO, 100 μm U73343 in DMSO, or 100 μm U73122 in DMSO. Changes are given as the percentage of the DMSO control. Data are the average of four independent experiments; the error is approximately 20%.