Figure 3.

The frequency of alteration of the RAC1 gene in lung cancers: The oncoprint presents data obtained from c-BioPortal (February 2019) representing a combined study of 1933 samples (http://www.cbioportal.org), querying 1933 patients/samples in six studies as shown in the different color codes of the oncoprint (upper panel) under “Study of origin” in the figure. The percentage (3%*) represents the alteration of the RAC1 gene in patients with lung cancers. The lower panel of the oncoprint represents the types of alterations of RAC1 gene in samples as shown under “Genetic Alteration” in the figure. The middle panel of the oncoprint presents distribution of metastatic stage (M Stage as shown in the figure) of the patients where alteration of the RAC1 gene was identified. Unaltered cases (RAC1 gene) were not included in the oncoprint. The bar diagram (figure on the right panel) represents the frequency of alterations in the RAC1 gene in a few individual lung cancer studies where alteration was identified. The Y-axis of the bar diagram represents alteration frequency of the RAC1 gene (colors represent the type of alteration as shown in the figure). The frequencies of alterations are sorted on the X-axis according to “Cancer Study”.