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Sexual reproduction and light sensing in A. nidulans. Darkness: VeA and VelB interact with the importin protein, KapA. This allows their transport into the nucleus where they regulate gene expression and initiate sexual development. Light: FphA, the red light sensor, interacts with VeA, putatively inhibiting its interaction with KapA and VelB. This prevents the transport of VeA into the nucleus. Instead, VelB interacts with other proteins, activating asexual reproduction.
