Table 2.
Survival analysis.
| Parameter | Univariate | Multivariate | |
|---|---|---|---|
| p | HR (95% CI) | p | |
| OS | |||
| Hypopharynx | >0.001 | 1.3596 (0.7103–2.6025) | 0.3538 |
| Oropharynx | 0.0314 | 0.7232 (0.3910–1.3376) | 0.3017 |
| T 3,4 vs. T 1,2 | 0.0486 | 1.5954 (0.9483–2.6843) | 0.0784 |
| N 2,3 vs. N 0,1 | 0.00776 | 1.7314 (0.9869–3.0374) | 0.0556 |
| Palliative Treatment | >0.001 | 3.6380 (1.2499–10.5885) | 0.0178 |
| Primary RT/CT | 0.0258 | 1.1562 (0.4655–2.8715) | 0.7545 |
| Surgery with adjuvant RT/CT | >0.001 | 0.3771 (0.1375–1.0338) | 0.0580 |
| Alanine | 0.00482 | 0.7182 (0.4138–1.2467) | 0.2395 |
| Cystine | 0.0331 | 1.0765 (0.6204–1.8679) | 0.7932 |
| Methionine | >0.001 | 0.5248 (0.3056–0.9013) | 0.0195 |
| RFS | |||
| Oral Cavity | 0.0223 | 4.6898 (1.49124–14.7489) | 0.00820 |
| Oropharynx | 0.00292 | 0.2998 (0.09951–0.9034) | 0.03232 |
| Primary RT/CT | 0.0181 | 5.1464 (1.89193–13.9992) | 0.00133 |
| Threonine | 0.033 | 0.2893 (0.06630–1.2623) | 0.09892 |
| Methionine | 0.0136 | 0.4373 (0.19240–0.9941) | 0.04836 |
OS, 5-year overall survival (OS); RFS, 5-year relapse free survival; HR, hazard ratio.