Skip to main content
. 2019 Apr 27;8(5):386. doi: 10.3390/cells8050386

Table 5.

List of up-regulated (left) and down-regulated (right) identified proteins from the “antigen processing and presentation of peptide antigen via MHC class II”, “proteasome-mediated ubiquitin-dependent protein catabolic process” and “proteasome” pathways. Protein FDR P values were < 0.001. Protein symbols correspond to homologue Homo sapiens proteins identified by sequence homology using Blast2GO.

Antigen Processing and Presentation of Peptide Antigen via MHC Class II Proteasome-mediated Ubiquitin-Dependent Protein Catabolic Process Proteasome
Upr.
Protein
Log2 Fold Downr.
Protein
Log2 Fold Upr.
Protein
Log2 Fold Downr.
Protein
Log2 Fold Upr.
Protein
Log2 Fold Downr.
Protein
Log2 Fold
ACTR1B 3.37 CAPZB −2.68 CD2AP 7.50 HSPA5 −6.23 PSMB3 4.44 PSMA1 −5.33
AP2S1 5.75 CLTC −3.69 DDB1 3.32 PSMA1 −5.33 PSMB6 3.73 PSMA2 −5.43
CLTA 4.51 RAB7A −4.69 GCLC 4.63 PSMA2 −5.43 PSMC2 2.98 PSMA3 −3.31
DNM2 5.32 HSPA1A 4.74 PSMA3 −3.31 PSMD13 2.26 PSMA4 −4.78
DYNC1H1 5.43 NPLOC4 1.68 PSMA4 −4.78 PSMD2 3.98 PSMA5 −6.15
KIF15 3.89 PLAA 5.08 PSMA5 −6.15 PSMD4 5.83 PSMA6 −6.49
PYCARD 3.28 PSMB3 4.44 PSMA6 −6.49 PSME1 5.73 PSMA8 −5.50
PSMB6 3.73 PSMA8 −5.50 PSMB1 −4.45
PSMC2 2.98 PSMB1 −4.45 PSMB2 −5.29
PSMD13 2.26 PSMB2 −5.29 PSMB4 −3.69
PSMD2 3.98 PSMB4 −3.69 PSME2 −3.44
PSMD4 5.83 PSME2 −3.44
PSME1 5.73 RAD23B −3.77
RACK1 3.95 UBC −5.19
RAD23A 4.85 UBR2 −11.48
RPS27A 5.03 VCP −2.86
UBB 4.39 WFS1 −10.33
USP19 8.29
YOD1 2.95