Table 1.
No. of Patients | (a) Serum HBV DNA | (b) Intrahepatic Total HBV DNA | (c) Intrahepatic cccDNA | Year | Country Where the Patients Were Enrolled | References | |||
---|---|---|---|---|---|---|---|---|---|
Correlation Coefficient | p Value | Correlation Coefficient | p Value | Correlation Coefficient | p Value | ||||
82 | Total: 0.807 | <0.001 | 2003 | Japan | [33] | ||||
HBeAg-positive: 0.847 | <0.001 | ||||||||
HBeAg-negative:0.632 | <0.001 | ||||||||
190 | 0.79 (HBV genotype B) | <0.001 | 2005 | Japan | [41] | ||||
0.87 (HBV genotype C) | <0.001 | ||||||||
93 | 0.82 | <0.001 | 0.7 | <0.001 | 0.664 | <0.001 | 2007 | Japan | [40] |
31 | 0.482 | <0.006 | 2009 | Japan | [34] | ||||
138 | Total: 0.69 | <0.0001 | 0.7 | <0.0001 | 2017 | Hong Kong | [42] | ||
HBeAg-positive: 0.66 | <0.0001 | ||||||||
HBeAg-negative:0.59 | <0.0001 | ||||||||
305 | 0.67 | <0.001 | 2017 | Hong Kong | [42] | ||||
79 of 82* | 0.323 | 0.004 | 2019 | China | [46] |