Table 2.

Relationship between HBcrAg and other HBV markers through chronic hepatitis B (CHB) natural history.

Disease Phase	HBeAg	No. of Patients	Serum HBV DNA		Serum HBsAg		Serum HBsAg-HQ		Year	Country Where the Patients Were Enrolled	References
			Correlation Coefficient	p Value	Correlation Coefficient	p Value	Correlation Coefficient	p Value
Immune tolerance	Positive	30	0.45	0.013	0.47	0.0095			2015	Germany	[35]
		52	0.369	0.007	0.286	0.04	0.401	0.003	2014	Hong Kong	[25]
Immune clearance	Positive	60	0.66	<0.0001	0.53	<0.0001			2015	Germany	[35]
		105	0.484	<0.001	0.406	0.017	0.596	0.401	2014	Hong Kong	[25]
Hepatitis	Negative	50	0.74	<0.0001	0.4	0.0045			2015	Germany	[35]
		97	0.537	<0.001	0.245	<0.001	0.401	<0.001	2014	Hong Kong	[25]
Inactive/quiescent carrier	Negative	109	0.18	0.054	0.47	<0.0001			2015	Germany	[35]
		95	0.472	<0.001	0.388	<0.001	0.605	<0.001	2014	Hong Kong	[25]