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. 2019 May 11;11(5):653. doi: 10.3390/cancers11050653

Figure 3.

Figure 3

Effect of metformin on endometrial cancer stem cell number and activity. (a) On the left, SFE of Ishikawa cells treated with metformin in non-adherent culture. On the right, SFE of Hec-1a cells treated with metformin (n = 3). (b) On the left, the proportion of ALDHhigh cells following treatment of Ishikawa and Hec-1a cells with metformin. On the right, the proportion of CD133+ve Ishikawa cells following treatment with metformin (n = 5). Data are represented as mean ± SEM. * p ≤ 0.05, ** p ≤ 0.01, ** p ≤ 0.001, **** p ≤ 0.0001.