Table 2.
List of the first 20 differentially expressed transcripts in cecum of broiler chickens ranked by fold change ratio (FCR), compared to the jejunal mucosa.
| Fold Change Ratio 1 | p-Value | FDR p-Value 2 | Gene Symbol 3 | Description |
|---|---|---|---|---|
| 244.4 | 6.17 × 10−21 | 4.18 × 10−18 | CBS | cystathionine-beta-synthase |
| 121.2 | 1.44 × 10−21 | 1.55 × 10−18 | ENSGALG00000021450 | C factor like |
| 78.4 | 1.19 × 10−23 | 7.73 × 10−20 | MAL | mal, T-cell differentiation protein |
| 40.8 | 1.42 × 10−19 | 4.34 × 10−17 | AQP8 | aquaporin 8 |
| 24.5 | 6.06 × 10−16 | 6.60 × 10−14 | NOXO1 | NADPH oxidase organizer 1 |
| 22.5 | 1.76 × 10−14 | 1.24 × 10−12 | CA4 | carbonic anhydrase IV |
| 18.0 | 3.58 × 10−18 | 7.28 × 10−16 | HOXA10 | homeobox A10; homeobox protein Hox-A10-like |
| 17.9 | 3.44 × 10−20 | 1.40 × 10−17 | SLC38A4 | solute carrier family 38, member 4 (SNAT4) |
| 15.8 | 2.11 × 10−15 | 2.01 × 10−13 | SLC26A4 | solute carrier family 26 (anion exchanger), member 4 |
| 15.1 | 5.97 × 10−22 | 7.80 × 10−19 | PON2 | paraoxonase 2 |
| 14.2 | 4.79 × 10−15 | 4.14 × 10−13 | TFCP2L1 | transcription factor CP2-like 1 |
| 14.2 | 2.93 × 10−21 | 2.55 × 10−18 | SELENBP1 | selenium binding protein 1; selenium-binding protein 1-A-like |
| 14.0 | 7.89 × 10−15 | 6.28 × 10−13 | ATP6V0D2 | ATPase, H+ transporting, lysosomal 38 kDa, V0 subunit d2 |
| 13.2 | 3.34 × 10−20 | 1.39 × 10−17 | PADI3 | peptidyl arginine deiminase, type III |
| 12.9 | 5.97 × 10−15 | 4.99 × 10−13 | PLET1 | Placenta expressed transcript 1 |
| 12.9 | 3.03 × 10−14 | 2.05 × 10−12 | GJB2 | gap junction protein, beta 2, 26 kDa |
| 12.0 | 8.16 × 10−18 | 1.57 × 10−15 | LY6E | lymphocyte antigen 6 complex, locus E-like |
| 11.7 | 1.74 × 10−16 | 2.28 × 10−14 | gga-mir-196-4 | microRNA 196-4 |
| 11.2 | 8.74 × 10−17 | 1.25 × 10−14 | GSTA4 | glutathione S-transferase alpha 4 |
| 11.0 | 2.26 × 10−23 | 1.03 × 10−19 | B4GALNT3 | beta-1,4-N-acetyl-galactosaminyltransferase 3 |
1,2 Affymetrix transcripts were considered as differentially expressed transcripts (DETs) when showing a ≥2-fold change ratio (FCR) and a false discovery rate (FDR) < 0.05 between tissues. 3 Transcripts were annotated based on Gallus gallus Ensembl (release 85, www.ensembl.org). The full list of differentially expressed genes is reported in Table S3 (Supplementary Materials).