Table 3. . Univariate association of clinical variables with paclitaxel T_{c >0.05} and C_max.

Clinical variables	Associations with Tc >0.05		Associations with Cmax
	B coefficient (95% CI)	p-value	B coefficient (95% CI)	p-value
Age (years)	1.00 (0.99–1.00)	0.90	15.15 (1.88–28.42)	0.026
BSA (m2)	1.27 (0.96–1.68)	0.10	-262.77 (-1085.39–559.85)	0.52
Caucasian race (vs other)	1.22 (0.97–1.53)	0.09	-387.50 (-1051.95–276.95)	0.25
Elevated alkaline phosphatase (vs normal)	0.90 (0.76–1.06)	0.22	-83.33 (-577.99–411.32))	0.74
Elevated ALT or AST (vs normal)	1.09 (0.90–1.32)	0.38	261.13 (-294.55–816.81)	0.35
Elevated albumin (vs normal)	0.86 (0.55–1.35)	0.52	356.18 (-948.61–1660.98)	0.59
Prior or concurrent chemotherapy (vs none)	1.03 (0.82–1.30)	0.79	-503.46 (-1260.63–253.71)	0.19
Prior or concurrent HER2 therapy (vs none)	1.02 (0.91–1.15)	0.75	136.26 (-208.52–481.03)	0.43

BSA: Body surface area; SD: Standard deviation.