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. 2019 May 8;17(5):272. doi: 10.3390/md17050272

Figure 2.

Figure 2

Comparison of the four phlorotannins isolated from ECE on EC adhesion molecule expression and cell survival in vitro. (A) Illustration explains palmitate induced EC dysfunction model in vitro. (B–E) mRNA expression levels of the adhesion molecules, including E-selsectin, ICAM-1, VCAM-1 and vWF in ECs as determined by qRT-PCR. (F) The graph shows PA with or without phlorotannin (dieckol (DK), 2,7-phloroglucinol-6,6-bieckol (PHB), Pyrogallol-Phloroglucinol-6,6-Bieckol (PPB), and phlorofucofuroeckol A (PFFA)) treated EC survival ratio. *, P < 0.05 and **, P < 0.01 vs. the PBS group; $, P < 0.05 and $$, P < 0.01 vs. PA/PBS group; #, P < 0.05 vs. PA/PPB. PA, palmitate conjugation to BSA; DK, dieckol; PHB, 2,7-phloroglucinol-6,6-bieckol; PPB, pyrogallol-phloroglucinol-6,6-bieckol; PFFA, phlorofucofuroeckol A.