Figure 3.

TN is an efficient activator of arachidonoylethanolamine and palmitamide upregulation. Human pulmonary artery smooth muscle cells were treated with either TN (100 µM) or TA (100 µM) plus niacin (100 µM) (TA + N) for 10 min. Samples were subjected to metabolomics analysis. (A) Arachidonoylethanolamine and (B) palmitamide were found to be differentially expressed between TN and TA + N groups. Bar graphs represent the mean ± SEM values of signal intensity. * Values are significantly different from each other at p < 0.05 (n = 9).