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In vitro release behavior of different edaravone loaded formulations using a dialysis bag method in phosphate buffer (pH 5) at 37 °C. The edaravone concentrations were measured by high performance liquid chromatography (mean ± SD, n = 3, *** p < 0.005: EDA-NP vs. EDA-NP-gel and free EDA **** p < 0.001: free EDA vs. EDA-NP-gel).
