MSCs	mesenchymal stem cells
αSMA	alpha-smooth muscle actin-expressing
mSCN	mesenchymal stem cell niche
Shh	sonic hedgehog
PDAC	pancreatic adenocarcinoma
CAFs	cancer-associated fibroblasts
PSCs	pancreatic stellate cells
MMPs	matrix metalloproteinases
ECM	extracellular matrix
MDT	moderately differentiated tumour
PDT	poorly differentiated tumour
ROI	regions of interest
FDM	free differentiation medium
PDM	preventing differentiation medium
3D-TGA	three-dimensional tumour growth assay
qRT-PCR	quantitative real-time polymerase chain reaction
IHC	immunohistochemistry