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. 2019 Apr 30;10(5):328. doi: 10.3390/genes10050328

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Phylogenetic relationships based on the inferred protein sequences of the A domain from the monomodular NRPS gene examined in this study. The panel to the right indicates the domain structure of the NRPS genes in the respective clusters. The tree was inferred using the neighbor-joining (NJ) method in MEGA v.7 with the LG + I + G + F model. Similar groupings were obtained using maximum likelihood (ML) analysis and the same model parameters. Branch support is indicated at the internodes (>50% bootstrap values based on a 1000 repeats) in the order NJ/ML.