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. 2019 Feb 12;21(6):e13011. doi: 10.1111/cmi.13011

Figure 6.

Figure 6

Summary of known regulatory events that contribute to the control of microneme and dense granule exocytosis. Chemical agonists (green) of secondary messengers cGMP and Ca2+ and antagonists (red) of these messengers or kinases used in this study are shown. Microneme interaction and fusion at the plasma membrane via APH‐PA interactions and Ca2+‐dependent DOC2.1 activity is also shown. APH: acylated pleckstrin‐homology; (PH) domain‐containing protein; CDPK: Ca2+‐dependent protein kinase; DAG: diacylglycerol; PA: phosphatidic acid; PKG: protein kinase G