Table 7.
Pairwise comparison of Coronaviridae-wide conserved domains in replicase polyprotein 1ab and overall replicase polyprotein 1ab between Tr-BatCoV HKU33 strain GZ151867 and other alphaCoVs.
| Replicase Polyprotein Domain | Pairwise Amino Acid Sequence Identity with Tr-BatCoV HKU33 Strain GZ151867 (%) | ||||
|---|---|---|---|---|---|
| BtNv-AlphaCoV/SC2013 | BtRf-AlphaCoV/HuB2013 | BtMs-AlphaCoV/GS2013 | AlphaCoV BatCoV/P.kuhlii/Italy 206679-3/2010 |
Rs-BatCoV HKU32 Strain TLC28A | |
| nsp3 | 58.8 | 48.7 | 48.8 | 57.3 | 49.0 |
| nsp5 | 82.5 | 74.2 | 74.5 | 78.8 | 75.2 |
| nsp12 | 86.3 | 83.5 | 83.6 | 86.4 | 83.7 |
| nsp13 | 87.0 | 79.7 | 80.1 | 82.7 | 80.9 |
| nsp14 | 84.0 | 79.3 | 79.3 | 82.4 | 78.8 |
| nsp15 | 85.8 | 79.6 | 79.0 | 84.7 | 78.2 |
| nsp16 | 87.3 | 80.8 | 80.5 | 84.2 | 81.2 |
| 7 Concatenated Domains | 76.3 | 69.2 | 69.1 | 74.4 | 69.4 |
| Overall replicase pp1ab | 73.4 | 62.9 | 63.0 | 71.6 | 63.3 |