Table 2.
Characteristics Female Dorsett Sheep at Each Time Point
| Baseline (n=5) | Postvalvectomy (n=5) | hTPV+1 mo (n=5) | hTPV+5 mo (n=5) | hTPV+8 mo (n=5) | |
|---|---|---|---|---|---|
| Weight, kg | 37.2±2.3 | 40.0±3.6 | 54.2±8.1 | 66.4±10.1 | 73.8±10.5 |
| BSA, m2 | 1.0±0.0 | 1.1±0.1 | 1.3±0.1 | 1.5±0.2 | 1.6±0.2 |
| iRVEDV, mL/m2 | 62.3±7.5 | 93.1±15.3 | 79.4±17.7 | 74.5±12.6 | 65.1±17.9 |
| iRVESV, mL/m2 | 17.0±3.0 | 45.4±20.3 | 46.3±20.0 | 36.1±14.3 | 29.4±13.1 |
| iRVSV, mL/m2 | 45.3±8.6 | 47.7±17.7 | 33.2±2.9 | 38.4±7.0 | 33.4±9.1 |
| RVEF, % | 72.3±7.2 | 51.6±17.0 | 43.7±11.4 | 52.9±13.2 | 56.7±12.5 |
| iLVEDV, mL/m2 | 72.8±13.2 | 64.4±13.8 | 65.6±13.5 | 58.6±14.3 | 50.7±7.3 |
| iLVESV, mL/m2 | 27.3±8.8 | 32.6±17.3 | 30.5±16.9 | 26.6±13.5 | 20.1±5.2 |
| iLVSV, mL/m2 | 45.5±8.0 | 31.7±8.7 | 35.1±3.6 | 32.0±5.4 | 29.2±4.7 |
| LVEF, % | 62.9±8.4 | 51.3±15.2 | 55.4±14.7 | 56.4±11.6 | 58.0±10.4 |
| PRF, % | 0.2±0.5 | 40.5±10.0 | 8.3±2.4 | 10.6±6.6 | 8.6±6.0 |
Values are given in mean±SD. BSA indicates body surface area; hTPV, Harmony transcatheter pulmonary valve; iLVEDV, indexed left ventricular end diastolic volume; iLVESV, indexed left ventricular end systolic volume; iLVSV, indexed left ventricular stroke volume; iRVEDV, indexed right ventricular end diastolic volume; iRVESV, indexed right ventricular end systolic volume; iRVSV, indexed right ventricular stroke volume; LVEF, left ventricular ejection fraction; PRF, pulmonary regurgitant fraction; and RVEF, right ventricular ejection fraction.