Fig. 6.

Inhibition of ERK, PI3K, and p38 resulted in decreased axonal outgrowth of CSMNs. a-d The axon length of CSMNs was measured and represented as a bar graph after treatment with U0126 (ERK inhibitor) (a), LY294002 (PI3K inhibitor) (b), SB203580 (p38 inhibitor) (c), and SP600125 (JNK inhibitor) (d). For bar graphs, values are represented as mean ± SEM. In Fig. 6a-d, one-way ANOVA was performed, followed by Tukey’s post-hoc test. ^*p < 0.05, ^**p < 0.01, ^***p < 0.001, ^****p < 0.0001, n.s. > 0.05