Table 1.
Protein expression and methylation status of SSTR5 in LSCC tumor tissues
| Groups | N | Protein expression | Methylation frequency (promoter) | Methylation frequency (Exon 1) | |||
|---|---|---|---|---|---|---|---|
| n (%) | P | n (%) | P | n (%) | P | ||
| Age | |||||||
| < 60 | 25 | 9 (36.0) | 4 (16.0) | 13 (52.0) | |||
| ≥ 60 | 23 | 7 (30.4) | 0.683 | 5 (21.7) | 0.611 | 14 (60.9) | 0.536 |
| Gender | |||||||
| Male | 46 | 15 (32.6) | 9 (19.6) | 26 (56.5) | |||
| Female | 2 | 1 (50.0) | 0.610 | 0 (0.0) | 0.488 | 1 (50.0) | 0.856 |
| Smoking | |||||||
| Negative | 10 | 4 (40.0) | 2 (20.0) | 5 (50.0) | |||
| Positive | 38 | 12 (31.6) | 0.615 | 7 (18.4) | 0.909 | 22 (57.9) | 0.654 |
| TNM stage | |||||||
| I + II | 19 | 10 (52.6) | 3 (15.8) | 7 (36.8) | |||
| III + IV | 29 | 6 (20.7) | 0.022 | 6 (20.7) | 0.671 | 20 (68.9) | 0.028 |
| Pathological differentiation of tumor | |||||||
| Well | 20 | 9 (45.0) | 3 (15.0) | 8 (40.0) | |||
| Moderate | 16 | 5 (31.3) | 3 (18.7) | 10 (62.5) | |||
| Poor | 12 | 2 (16.7) | 0.252 | 3 (25.0) | 0.782 | 9 (75.0) | 0.128 |
| LN metastasis | |||||||
| Negative (N0) | 22 | 11 (50.0) | 4 (18.2) | 8 (36.4) | |||
| Positive (N1/2/3) | 26 | 5 (19.2) | 0.024 | 5 (19.2) | 0.926 | 19 (73.1) | 0.011 |