Table 4. Results From Analysis Using the SCANDAT Database, Comparing Survival of Patients Transfused Before and After Female Donors Deliver Their First Child.
| Donor Parity | ||||
|---|---|---|---|---|
| Nulliparous | 1 Delivery | 2 Deliveries | ≥3 Deliveries | |
| Donor recipientsa | 78 594 | 39 383 | 19 275 | 4092 |
| Person-years | 54 542 | 26 437 | 12 558 | 2577 |
| Deaths | 32 219 | 16 278 | 7801 | 1640 |
| HR (95% CI)b | 1 [Reference] | 1.01 (0.99-1.03) | 1.01 (0.97-1.04) | 1.01 (0.94-1.08) |
Abbreviations: HR, hazard ratio; SCANDAT, Scandinavian Donations and Transfusions.
a
A total of 110 996 unique patients were included in this analysis, but because some patients received blood from more than 1 female donor who changed parity status, the sum is higher at 141 344.
b
HRs were calculated using a 2-step process, first adjusting for calendar year, hospital, patient age, patient sex, as well as patient Charlson comorbidity index and then considering the association of donor parity using a stratified Cox model, with the aforementioned adjustment included as an offset.