Table 2. Primary Outcomes: Intervention vs Control Group.
Characteristic | Intervention | Control | Intervention Effect (Adjusted) | |||||
---|---|---|---|---|---|---|---|---|
Value, Mean (SD) | Δ (95% CI)a | P Valuea | Value, Mean (SD) | Δ (95% CI)a | P Valuea | DiD (95% CI) |
P Value | |
Asthma Control Test score | ||||||||
Baseline | 14.8 (3.9) | 14.3 (4.0) | ||||||
3 mo | 16.2 (4.4) | 1.4 (0.8 to 2.0) | <.001 | 14.6 (4.8) | 0.4 (−0.5 to 1.2) | .58 | 1.2 (0.2 to 2.2) | .02 |
6 mo | 16.2 (4.4) | 1.4 (0.8 to 2.1) | <.001 | 14.6 (4.9) | 0.4 (−0.5 to 1.2) | .37 | 1.0 (0.0 to 2.1) | .049 |
12 mo | 17.1 (4.7) | 2.2 (1.5 to 2.9) | <.001 | 16.1 (4.3) | 1.5 (0.5 to 2.6) | <.001 | 0.6 (−0.5 to 1.8) | .28 |
Overall effectb | χ24 = 13.4 | .01 | ||||||
Mini Asthma Quality of Life score | ||||||||
Baseline | 4.3 (1.2) | 4.3 (1.1) | ||||||
3 mo | 4.7 (1.2) | 0.4 (0.2 to 0.5) | <.001 | 4.3 (1.3) | 0.0 (−0.2 to 0.2) | .91 | 0.4 (0.1 to 0.6) | .007 |
6 mo | 4.7 (1.3) | 0.3 (0.1 to 0.5) | <.001 | 4.3 (1.3) | −0.1 (−0.3 to 0.2) | .62 | 0.4 (0.1 to 0.7) | .02 |
12 mo | 4.8 (1.3) | 0.5 (0.3 to 0.7) | <.001 | 4.6 (1.3) | 0.3 (0.0 to 0.5) | .03 | 0.2 (−0.1 to 0.5) | .20 |
Overall effectb | χ24 = 10.5 | .03 | ||||||
Medication Adherence Rating scale score | ||||||||
Baseline | 3.6 (0.7) | 3.8 (0.7) | ||||||
3 mo | 3.9 (0.6) | 0.3 (0.2 to 0.4) | <.001 | 3.8 (0.7) | 0.1 (0.0 to 0.3) | .50 | 0.2 (0.1 to 0.4) | .01 |
6 mo | 3.9 (0.7) | 0.3 (0.2 to 0.4) | <.001 | 3.8 (0.8) | 0.0 (−0.1 to 0.2) | .69 | 0.2 (0.0 to 0.4) | .02 |
12 mo | 3.9 (0.7) | 0.3 (0.1 to 0.4) | <.001 | 3.8 (0.7) | 0.1 (−0.1 to 0.2) | .70 | 0.3 (0.1 to 0.5) | .01 |
Overall effectb | χ24 = 9.5 | .049 | ||||||
MDI technique, % correctly completed steps, median (range) | ||||||||
Baseline | 56 (0 to 100) | 64 (9 to 100) | ||||||
12 mo | 75 (0 to 100) | 6 (−14 to 6) | .45 | 58 (0 to 100) | −16 (−1 to −31) | .04 | 15 (7 to 22) | .004 |
Patients with ≥1 emergency department visit, % | ||||||||
Baseline | 10.5 | 9.7 | ||||||
12 mo | 6.2 | 0.9 (0.7 to 1.0)c | .02 | 12.7 | 1.1 (0.9 to 1.3)c | .33 | 0.8 (0.6 to 0.99)c | .03 |
Abbreviations: DiD, difference-in-differences; MDI, metered-dose inhaler.
Change within study arm relative to baseline.
Effect over all time points.
Odds ratio.