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. 2019 Jun 12;4(7):628–635. doi: 10.1001/jamacardio.2019.1746

Table 3. Association Between Hypertensive Pregnancy Disorders and Cardiovascular Disease and BMI, Blood Pressure, and Serum Glucose and Lipid Levels in Women Aged 40 to 70 Years.

Cardiovascular Risk Factors Women, No. Total Association Between HDP and CVD Part of Association Between HDP and CVD That Is Not Associated With the Examined Cardiovascular Risk Factors Part of Association Between HDP and CVD That Is Associated With the Examined Cardiovascular Risk Factors Proportion of Excess Cardiovascular Risk in Women Who Had HDP That Is Associated With Cardiovascular Risk Factor(s), %b
HR (95% CI)a P Value HR (95% CI)a P Value HR (95% CI)a P Value
BMI 23 508 1.54 (1.29-1.83) <.001 1.29 (1.06-1.56) .01 1.19 (1.07-1.33) .001 41
Systolic blood pressure 23 500 1.55 (1.29-1.86) <.001 1.19 (0.97-1.47) .10 1.30 (1.16-1.47) <.001 60
Diastolic blood pressure 23 501 1.55 (1.30-1.85) <.001 1.13 (0.92-1.38) .25 1.38 (1.23-1.55) <.001 73
Glucose 21 881 1.58 (1.30-1.92) <.001 1.40 (1.15-1.72) .001 1.12 (1.02-1.23) .01 25
Non-HDL cholesterol 21 517 1.53 (1.26-1.88) <.001 1.38 (1.12-1.69) .002 1.11 (1.02-1.21) .02 24
BMI and systolic blood pressure 23 453 1.53 (1.27-1.84) <.001 1.15 (0.91-1.44) .23 1.33 (1.16-1.53) <.001 67
BMI and diastolic blood pressure 23 454 1.53 (1.28-1.83) <.001 1.09 (0.88-1.36) .43 1.40 (1.22-1.61) <.001 79

Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); CVD, cardiovascular disease; HDL, high-density lipoprotein; HDP, hypertensive disorders of pregnancy.

a

Estimates are adjusted for age, highest obtained educational level, ever smoked daily, parity at younger than age 40 years, maternal birth year, and family history of coronary heart disease.

b

We calculated the percentage excess risk associated with each risk factor by dividing the β coefficient for the part of the association between HDP and CVD that was associated with the cardiovascular risk factor(s) with the β coefficient for the total association between HDP and CVD.