Table 4.
Phylogenetic group relation with virulence factors and islands of pathogenicity of 48 blood Escherichia coli isolates, 2015–2018.
| Virulence factor, n (%) | Gene | Phylogenetic groups | Total (n = 48) | p-value | |
|---|---|---|---|---|---|
| B2 (n = 22) | Non-B2 (n = 26) | ||||
| Type 1 fimbrial adhesin | fimH | 21 (45.7) | 25 (54.3) | 46 (95.8) | - |
| Outer membrane lipoprotein | traT | 19 (51.4) | 18 (48.6) | 37 (77.1) | - |
| Yersiniabactin siderophore receptor | fyuA | 21 (61.8) | 13 (38.2) | 34 (70.8) | 0.001 |
| Aerobactin siderophore receptor | iutA | 17 (54.8) | 14 (45.2) | 31 (64.3) | - |
| Group capsular II | kpsMT II | 18 (81.8) | 4 (18.2) | 22 (45.8) | 0.001 |
| Salmochelin siderophore receptor | iroN | 11 (61.1) | 7 (38.9) | 18 (37.5) | - |
| P fimbriae C | papC | 14 (82.4) | 3 (17.6) | 17 (35.4) | <0.001 |
| Colicin C | cvaC | 8 (53.3) | 7 (46.7) | 15 (31.3) | - |
| Outer membrane protease | ompT | 3 (30.0) | 7 (70.0) | 10 (20.8) | - |
| K5 capsule | kpsMT K5 | 9 (90.0) | 1 (10.0) | 10 (20.8) | 0.002 |
| Haemolysin F | hlyF | 3 (30.0) | 7 (70.0) | 10 (20.8) | - |
| Increased serum survival | iss | 3 (30.0) | 7 (70.0) | 10 (20.8) | - |
| Haemolysin A | hlyA | 7 (100.0) | - | 7 (14.6) | 0.002 |
| Cytotoxic necrotizing factor 1 | cnf1 | 6 (100.0) | - | 6 (12.5) | 0.004 |
| Adhesin Afa | afa | 3 (60.0) | 2 (40.0) | 5 (10.4) | - |
| K1 capsule | kpsMT K1 | 4 (100.0) | - | 4 (8.3) | 0.023 |
| S fimbriae (S) | sfaS | 3 (100.0) | - | 3 (6.3) | - |
| S fimbriae (A) | sfaA | 2 (100.0) | - | 2 (4.2) | - |
| Invasion of brain endothelium | ibeA | 1 (50.0) | 1 (50.0) | 2 (4.2) | - |
| Group capsular III | kpsMT III | - | 1 (100.0) | 1 (2.1) | - |
| Cytotoxic necrotizing factor 2 | cnf2 | - | - | - | - |
| P fimbriae (G) | papG | - | - | - | - |
| PATHOGENICITY ISLANDS, n (%) | |||||
| PAI IV536 | 21(56.8) | 16 (43.2) | 37 (77.1) | 0.005 | |
| PAI ICFT073 | 22 (88.0) | 3 (12.0) | 25 (52.1) | <0.001 | |
| PAI IICFT073 | 12 (92.3) | 1 (7.7) | 13 (27.1) | <0.001 | |
| PAI I536 | 6 (100.0) | - | 6 (12.5) | 0.010 | |
| PAI IIJ96 | 5 (100.0) | - | 5 (10.4) | 0.010 | |
| PAI II536 | 3 (100.0) | - | 3 (6.3) | - | |
| PAI III536 | 2 (100.0) | - | 2 (4.2) | - | |
| PAI IJ96 | - | - | - | - | |
Chi square test. Data expressed as absolute number (%).