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. 2019 Jun 6;10:1300. doi: 10.3389/fimmu.2019.01300

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Copyright © 2019 Solders, Gorchs, Tiblad, Gidlöf, Leeansyah, Dias, Sandberg, Magalhaes, Lundell and Kaipe.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Chemokine profile in intervillous blood is distinct from that of peripheral blood. (A) Heatmap displaying the levels of chemokines and cytokines (pg/ml plasma) in all individual samples of peripheral (PB) and intervillous blood (IVB) (n = 25). The brackets indicate significant differences between PB and IVB. Numbers indicate individual donors. (B) The levels of MIF, CXCL10, CXCL9, and CCL25 were significantly higher in IVB compared to PB, whereas the levels of CCL27, CXCL12, and CCL21 where significantly lower. Line in graphs represents the median. Comparisons between paired samples were made using the nonparametric Wilcoxon test. ^****p < 0.0001.