Table II.
Mutation status of Escherichia coli isolates at topoisomerase targets
| Total number of mutations | Number (%) of isolates | Alterations detected by MAMA-PCR | |||||
|---|---|---|---|---|---|---|---|
| gyrA 83 | gyrA 87 | parC 80 | parC 84 | gyrB 447 | parE 416 | ||
| 1 | 9 (20.93) | Mutation | None | None | None | None | None |
| 1 (2.32) | None | Mutation | None | None | None | None | |
| 2 | 4 (9.30) | Mutation | None | Mutation | None | None | None |
| 2 (4.65) | Mutation | Mutation | None | None | None | None | |
| 4 (9.30) | Mutation | None | None | Mutation | None | None | |
| 3 | 13 (30.23) | Mutation | Mutation | Mutation | None | None | None |
| 4 | 1 (2.32) | Mutation | Mutation | Mutation | Mutation | None | None |
MAMA, mismatch amplification mutation assays