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. 2019 Jun 10;7:e7091. doi: 10.7717/peerj.7091

Figure 5. Correlations and validations of EMT markers with SERPINE1 in gastric cancer.

Figure 5

The pearson correlations between SERPINE1 and the EMT markers, including (A) TWIST1, (B) TWIST2, (C) CDH2, and (D) FN1, in the TCGA STAD dataset. The gastric cancer (E) MGC803 and (F) AGS cells were treated with 50 and 100 μM Tiplaxtinin for 12 h. The mRNA expression of TWIST1, TWIST2, CDH2, and FN1 were examined by qRT-PCR. The gene expression was normalized to GAPDH. *p < 0.05, **p < 0.01, ***p < 0.001; ns, no statistical significance. Data were mean ± SD. Data were the representatives of three independent experiments.