Table 2.

Hydrothiolation of 1a with Various Thiols^a

^aReaction conditions: 1a (0.4 mmol), 2 (0.2 mmol), Rh(cod)₂SbF₆ (1 mol%), L5 (1 mol%), DCE (0.4 mL), 30 °C, 5 h. Isolated yields. Regioselectivity ratio (rr) is the ratio of 3 to 4, which is determined by ¹H NMR analysis of reaction mixture. Enantioselectivity determined by chiral SFC.

^b18:1 rr.