Table 1.
Frequency of endothelialisation and thrombotic metrics across stent platforms (swine coronaries).
| 3 days (Yorkshire, n=3) | 30 days (Yorkshire, n=9) | 90 days (Yucatan, n=7) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| UHS (n=4) | BMS (n=4) | DES (N/A) | UHS (n=8) | BMS (n=8) | DES (n=8) | UHS (n=7) | BMS (n=6) | DES (n=6) | |
| Endothelialisation score=4 (optimal result) | 0% | 0% | N/A | 100% | 100% | 62% | 100% | 100% | 100% |
| Endothelialisation score 3–4 | 100% | 75% | N/A | 0% | 0% | 25%** | 0% | 0% | 0% |
| Endothelialisation score <3 | 0% | 25%* | N/A | 0% | 0% | 13%** | 0% | 0% | 0% |
| Platelet adhesion score=0 (optimal result) | 100% | 75% | N/A | 100% | 100% | 62% | 100% | 100% | 100% |
| Platelet adhesion score 0–1 | 0% | 25%* | N/A | 0% | 0% | 13%** | 0% | 0% | 0% |
| Platelet adhesion score >1 | 0% | 0% | N/A | 0% | 0% | 25%** | 0% | 0% | 0% |
| Fibrin score=0 (optimal result) | 0% | 0% | N/A | 38% | 25% | 0% | 72% | 83% | 50% |
| Fibrin score 0–1 | 100% | 100% | N/A | 62% | 75% | 38% | 28% | 17% | 50% |
| Fibrin score >1 | 0% | 0% | N/A | 0% | 0% | 62% | 0% | 0% | 0% |
* and **:
same single BMS resp. DES devices missing optimal scores in both endothelialisation and platelet adhesion. Score definition. Endothelialisation (0–4) score 4: 100% confluent coverage, score 3: >75% coverage. Thrombotic (0–3) score 0: no platelet adhesion, 1: minimal platelet adhesion. Neointimal fibrin deposition (0–3) score 0: fibrin absent; score 1: infrequent fibrin deposition.
Bold: significant sample percentage showing suboptimal score compared to UHS13.